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MDH1-COMMD1 Gene Fusion FISH Probe

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Catalog: GFFP-MDH1/COMMD1-07132
Classification: Gene Fusion FISH Probes
Description: The MDH1-COMMD1 Gene Fusion FISH Probecan detect the fusion of MDH1 and COMMD1 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: MDH1-COMMD1 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Malate Dehydrogenase 1
Gene Summary 1 This gene encodes an enzyme that catalyzes the NAD/NADH-dependent, reversible oxidation of malate to oxaloacetate in many metabolic pathways, including the citric acid cycle. Two main isozymes are known to exist in eukaryotic cells: one is found in the mitochondrial matrix and the other in the cytoplasm. This gene encodes the cytosolic isozyme, which plays a key role in the malate-aspartate shuttle that allows malate to pass through the mitochondrial membrane to be transformed into oxaloacetate for further cellular processes. Alternatively spliced transcript variants have been found for this gene. A recent study showed that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Pseudogenes have been identified on chromosomes X and 6. [provided by RefSeq, Feb 2016]
Chromosome 1 Chromosome 2
Locus 1 2p15
Coordinates 1 This gene maps to 63815742-63834330 in GRCh37 coordinates.
Gene Name 2 Copper Metabolism Domain Containing 1
Gene Summary 2 COMMD1 is a regulator of copper homeostasis, sodium uptake, and NF-kappa-B (see MIM 164011) signaling (de Bie et al., 2005 [PubMed 16267171]).[supplied by OMIM, Sep 2009]
Chromosome 2 Chromosome2
Locus 2 2p15
Coordinates 2 This gene maps to 62132802-62363205 in GRCh37 coordinates.
Associated Diseases Breast Invasive Carcinoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-MDH1/COMMD1-07132-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-MDH1/COMMD1-07132-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-MDH1/COMMD1-07132-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-MDH1/COMMD1-07132-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-MDH1/COMMD1-07132-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-MDH1/COMMD1-07132-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-MDH1/COMMD1-07132-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-MDH1/COMMD1-07132-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-MDH1/COMMD1-07132-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-MDH1/COMMD1-07132-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-MDH1/COMMD1-07132-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-MDH1/COMMD1-07132-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-MDH1/COMMD1-07132-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-MDH1/COMMD1-07132-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-MDH1/COMMD1-07132-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-MDH1/COMMD1-07132-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-MDH1/COMMD1-07132-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-MDH1/COMMD1-07132-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-MDH1/COMMD1-07132-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-MDH1/COMMD1-07132-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-MDH1/COMMD1-07132-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-MDH1/COMMD1-07132-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-MDH1/COMMD1-07132-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-MDH1/COMMD1-07132-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-MDH1/COMMD1-07132-AQAQ 467nm;467nm 418nm;418nm

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