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MAPKBP1-VPS39 Gene Fusion FISH Probe

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Catalog: GFFP-MAPKBP1/VPS39-06874
Classification: Gene Fusion FISH Probes
Description: The MAPKBP1-VPS39 Gene Fusion FISH Probecan detect the fusion of MAPKBP1 and VPS39 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: MAPKBP1-VPS39 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Mitogen-activated Protein Kinase Binding Protein 1
Gene Summary 1 This gene encodes a scaffold protein that regulates the JNK (c-Jun N-terminal kinase) and NOD2 (nucleotide-binding oligomerization domain-containing protein 2) signaling pathways. The encoded protein interacts with another related JNK pathway scaffold protein, WDR62, via a conserved dimerization domain, and enhances JNK signaling. This protein may play a role in bacterial immunity by binding to the NOD2 receptor and negatively regulating downstream antibacterial and pro-inflammatory signaling. Mutations in this gene that impair cellular localization of the encoded protein cause a form of nephronophthisis, an autosomal-recessive kidney disorder, in human patients. [provided by RefSeq, May 2017]
Chromosome 1 Chromosome 15
Locus 1 15q15.1
Coordinates 1 This gene maps to 42066631-42120053 in GRCh37 coordinates.
Gene Name 2 VPS39, HOPS Complex Subunit
Gene Summary 2 This gene encodes a protein that may promote clustering and fusion of late endosomes and lysosomes. The protein may also act as an adaptor protein that modulates the transforming growth factor-beta response by coupling the transforming growth factor-beta receptor complex to the Smad pathway. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Chromosome 2 Chromosome15
Locus 2 15q15.1
Coordinates 2 This gene maps to 42450898-42500502 in GRCh37 coordinates.
Associated Diseases Bladder Urothelial Carcinoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-MAPKBP1/VPS39-06874-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-MAPKBP1/VPS39-06874-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-MAPKBP1/VPS39-06874-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-MAPKBP1/VPS39-06874-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-MAPKBP1/VPS39-06874-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-MAPKBP1/VPS39-06874-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-MAPKBP1/VPS39-06874-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-MAPKBP1/VPS39-06874-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-MAPKBP1/VPS39-06874-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-MAPKBP1/VPS39-06874-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-MAPKBP1/VPS39-06874-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-MAPKBP1/VPS39-06874-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-MAPKBP1/VPS39-06874-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-MAPKBP1/VPS39-06874-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-MAPKBP1/VPS39-06874-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-MAPKBP1/VPS39-06874-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-MAPKBP1/VPS39-06874-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-MAPKBP1/VPS39-06874-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-MAPKBP1/VPS39-06874-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-MAPKBP1/VPS39-06874-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-MAPKBP1/VPS39-06874-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-MAPKBP1/VPS39-06874-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-MAPKBP1/VPS39-06874-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-MAPKBP1/VPS39-06874-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-MAPKBP1/VPS39-06874-AQAQ 467nm;467nm 418nm;418nm

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