MAP4K3-EML4 Gene Fusion FISH Probe
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Catalog: |
GFFP-MAP4K3/EML4-14307 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The MAP4K3-EML4 Gene Fusion FISH Probecan detect the fusion of MAP4K3 and EML4 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
MAP4K3-EML4 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Mitogen-activated Protein Kinase Kinase Kinase Kinase 3 |
Gene Summary 1 |
This gene encodes a member of the mitogen-activated protein kinase kinase kinase kinase family. The encoded protein activates key effectors in cell signalling, among them c-Jun. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012] |
Chromosome 1 |
Chromosome 2 |
Locus 1 |
2p22.1 |
Coordinates 1 |
This gene maps to 39476421-39664219 in GRCh37 coordinates. |
Gene Name 2 |
Echinoderm Microtubule Associated Protein Like 4 |
Gene Summary 2 |
This gene is a member of the echinoderm microtubule associated protein-like family. The encoded WD-repeat protein may be involved in microtubule formation. Abnormal fusion of parts of this gene with portions of the anaplastic lymphoma receptor tyrosine kinase gene, which generates EML4-ALK fusion transcripts, is one of the primary mutations associated with non-small cell lung cancer. Alternative splicing of this gene results in two transcript variants. [provided by RefSeq, Jan 2015] |
Chromosome 2 |
Chromosome2 |
Locus 2 |
2p21 |
Coordinates 2 |
This gene maps to 42396489-42559688 in GRCh37 coordinates. |
Associated Diseases |
Head And Neck Squamous Cell Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-MAP4K3/EML4-14307-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-MAP4K3/EML4-14307-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-MAP4K3/EML4-14307-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-MAP4K3/EML4-14307-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-MAP4K3/EML4-14307-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-MAP4K3/EML4-14307-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-MAP4K3/EML4-14307-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-MAP4K3/EML4-14307-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-MAP4K3/EML4-14307-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-MAP4K3/EML4-14307-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-MAP4K3/EML4-14307-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-MAP4K3/EML4-14307-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-MAP4K3/EML4-14307-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-MAP4K3/EML4-14307-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-MAP4K3/EML4-14307-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-MAP4K3/EML4-14307-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-MAP4K3/EML4-14307-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-MAP4K3/EML4-14307-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-MAP4K3/EML4-14307-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-MAP4K3/EML4-14307-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-MAP4K3/EML4-14307-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-MAP4K3/EML4-14307-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-MAP4K3/EML4-14307-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-MAP4K3/EML4-14307-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-MAP4K3/EML4-14307-AQAQ |
467nm;467nm |
418nm;418nm |
|
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