LRP2-FASTKD1 Gene Fusion FISH Probe
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Catalog: |
GFFP-LRP2/FASTKD1-14274 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The LRP2-FASTKD1 Gene Fusion FISH Probecan detect the fusion of LRP2 and FASTKD1 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
LRP2-FASTKD1 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
LDL Receptor Related Protein 2 |
Gene Summary 1 |
The protein encoded by this gene, low density lipoprotein-related protein 2 (LRP2) or megalin, is a multi-ligand endocytic receptor that is expressed in many different tissues but primarily in absorptive epithilial tissues such as the kidney. This glycoprotein has a large amino-terminal extracellular domain, a single transmembrane domain, and a short carboxy-terminal cytoplasmic tail. The extracellular ligand-binding-domains bind diverse macromolecules including albumin, apolipoproteins B and E, and lipoprotein lipase. The LRP2 protein is critical for the reuptake of numerous ligands, including lipoproteins, sterols, vitamin-binding proteins, and hormones. This protein also has a role in cell-signaling; extracellular ligands include parathyroid horomones and the morphogen sonic hedgehog while cytosolic ligands include MAP kinase scaffold proteins and JNK interacting proteins. Recycling of this membrane receptor is regulated by phosphorylation of its cytoplasmic domain. Mutations in this gene cause Donnai-Barrow syndrome (DBS) and facio-oculoacoustico-renal syndrome (FOAR).[provided by RefSeq, Aug 2009] |
Chromosome 1 |
Chromosome 2 |
Locus 1 |
2q31.1 |
Coordinates 1 |
This gene maps to 169983618-170219122 in GRCh37 coordinates. |
Gene Name 2 |
FAST Kinase Domains 1 |
Gene Summary 2 |
The FAST Kinase Domains 1 (FASTKD1) gene is located on chr2 :170386262-170430424 at 2q31.1. |
Chromosome 2 |
Chromosome2 |
Locus 2 |
2q31.1 |
Coordinates 2 |
This gene maps to 170386262-170430424 in GRCh37 coordinates. |
Associated Diseases |
Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-LRP2/FASTKD1-14274-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-LRP2/FASTKD1-14274-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-LRP2/FASTKD1-14274-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-LRP2/FASTKD1-14274-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-LRP2/FASTKD1-14274-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-LRP2/FASTKD1-14274-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-LRP2/FASTKD1-14274-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-LRP2/FASTKD1-14274-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-LRP2/FASTKD1-14274-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-LRP2/FASTKD1-14274-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-LRP2/FASTKD1-14274-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-LRP2/FASTKD1-14274-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-LRP2/FASTKD1-14274-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-LRP2/FASTKD1-14274-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-LRP2/FASTKD1-14274-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-LRP2/FASTKD1-14274-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-LRP2/FASTKD1-14274-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-LRP2/FASTKD1-14274-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-LRP2/FASTKD1-14274-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-LRP2/FASTKD1-14274-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-LRP2/FASTKD1-14274-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-LRP2/FASTKD1-14274-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-LRP2/FASTKD1-14274-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-LRP2/FASTKD1-14274-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-LRP2/FASTKD1-14274-AQAQ |
467nm;467nm |
418nm;418nm |
|
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