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LRP2-FASTKD1 Gene Fusion FISH Probe

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Catalog: GFFP-LRP2/FASTKD1-14274
Classification: Gene Fusion FISH Probes
Description: The LRP2-FASTKD1 Gene Fusion FISH Probecan detect the fusion of LRP2 and FASTKD1 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: LRP2-FASTKD1 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 LDL Receptor Related Protein 2
Gene Summary 1 The protein encoded by this gene, low density lipoprotein-related protein 2 (LRP2) or megalin, is a multi-ligand endocytic receptor that is expressed in many different tissues but primarily in absorptive epithilial tissues such as the kidney. This glycoprotein has a large amino-terminal extracellular domain, a single transmembrane domain, and a short carboxy-terminal cytoplasmic tail. The extracellular ligand-binding-domains bind diverse macromolecules including albumin, apolipoproteins B and E, and lipoprotein lipase. The LRP2 protein is critical for the reuptake of numerous ligands, including lipoproteins, sterols, vitamin-binding proteins, and hormones. This protein also has a role in cell-signaling; extracellular ligands include parathyroid horomones and the morphogen sonic hedgehog while cytosolic ligands include MAP kinase scaffold proteins and JNK interacting proteins. Recycling of this membrane receptor is regulated by phosphorylation of its cytoplasmic domain. Mutations in this gene cause Donnai-Barrow syndrome (DBS) and facio-oculoacoustico-renal syndrome (FOAR).[provided by RefSeq, Aug 2009]
Chromosome 1 Chromosome 2
Locus 1 2q31.1
Coordinates 1 This gene maps to 169983618-170219122 in GRCh37 coordinates.
Gene Name 2 FAST Kinase Domains 1
Gene Summary 2 The FAST Kinase Domains 1 (FASTKD1) gene is located on chr2 :170386262-170430424 at 2q31.1.
Chromosome 2 Chromosome2
Locus 2 2q31.1
Coordinates 2 This gene maps to 170386262-170430424 in GRCh37 coordinates.
Associated Diseases Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-LRP2/FASTKD1-14274-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-LRP2/FASTKD1-14274-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-LRP2/FASTKD1-14274-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-LRP2/FASTKD1-14274-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-LRP2/FASTKD1-14274-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-LRP2/FASTKD1-14274-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-LRP2/FASTKD1-14274-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-LRP2/FASTKD1-14274-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-LRP2/FASTKD1-14274-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-LRP2/FASTKD1-14274-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-LRP2/FASTKD1-14274-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-LRP2/FASTKD1-14274-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-LRP2/FASTKD1-14274-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-LRP2/FASTKD1-14274-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-LRP2/FASTKD1-14274-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-LRP2/FASTKD1-14274-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-LRP2/FASTKD1-14274-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-LRP2/FASTKD1-14274-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-LRP2/FASTKD1-14274-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-LRP2/FASTKD1-14274-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-LRP2/FASTKD1-14274-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-LRP2/FASTKD1-14274-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-LRP2/FASTKD1-14274-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-LRP2/FASTKD1-14274-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-LRP2/FASTKD1-14274-AQAQ 467nm;467nm 418nm;418nm

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