LETM1-MXD4 Gene Fusion FISH Probe
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Catalog: |
GFFP-LETM1/MXD4-06332 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The LETM1-MXD4 Gene Fusion FISH Probecan detect the fusion of LETM1 and MXD4 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
LETM1-MXD4 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Leucine Zipper And EF-hand Containing Transmembrane Protein 1 |
Gene Summary 1 |
This gene encodes a protein that is localized to the inner mitochondrial membrane. The protein functions to maintain the mitochondrial tubular shapes and is required for normal mitochondrial morphology and cellular viability. Mutations in this gene cause Wolf-Hirschhorn syndrome, a complex malformation syndrome caused by the deletion of parts of the distal short arm of chromosome 4. Related pseudogenes have been identified on chromosomes 8, 15 and 19. [provided by RefSeq, Oct 2009] |
Chromosome 1 |
Chromosome 4 |
Locus 1 |
4p16.3 |
Coordinates 1 |
This gene maps to 1813205-1857974 in GRCh37 coordinates. |
Gene Name 2 |
MAX Dimerization Protein 4 |
Gene Summary 2 |
This gene is a member of the MAD gene family . The MAD genes encode basic helix-loop-helix-leucine zipper proteins that heterodimerize with MAX protein, forming a transcriptional repression complex. The MAD proteins compete for MAX binding with MYC, which heterodimerizes with MAX forming a transcriptional activation complex. Studies in rodents suggest that the MAD genes are tumor suppressors and contribute to the regulation of cell growth in differentiating tissues. [provided by RefSeq, Jul 2008] |
Chromosome 2 |
Chromosome4 |
Locus 2 |
4p16.3 |
Coordinates 2 |
This gene maps to 2249159-2263739 in GRCh37 coordinates. |
Associated Diseases |
Uterine Corpus Endometrial Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-LETM1/MXD4-06332-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-LETM1/MXD4-06332-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-LETM1/MXD4-06332-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-LETM1/MXD4-06332-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-LETM1/MXD4-06332-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-LETM1/MXD4-06332-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-LETM1/MXD4-06332-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-LETM1/MXD4-06332-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-LETM1/MXD4-06332-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-LETM1/MXD4-06332-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-LETM1/MXD4-06332-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-LETM1/MXD4-06332-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-LETM1/MXD4-06332-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-LETM1/MXD4-06332-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-LETM1/MXD4-06332-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-LETM1/MXD4-06332-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-LETM1/MXD4-06332-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-LETM1/MXD4-06332-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-LETM1/MXD4-06332-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-LETM1/MXD4-06332-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-LETM1/MXD4-06332-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-LETM1/MXD4-06332-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-LETM1/MXD4-06332-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-LETM1/MXD4-06332-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-LETM1/MXD4-06332-AQAQ |
467nm;467nm |
418nm;418nm |
|
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