KPNA1-GMPS Gene Fusion FISH Probe
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Catalog: |
GFFP-KPNA1/GMPS-06463 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The KPNA1-GMPS Gene Fusion FISH Probecan detect the fusion of KPNA1 and GMPS genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
KPNA1-GMPS Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Karyopherin Subunit Alpha 1 |
Gene Summary 1 |
The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC), which consists of 60-100 proteins. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion while larger molecules are transported by an active process. The protein encoded by this gene belongs to the importin alpha family, and is involved in nuclear protein import. This protein interacts with the recombination activating gene 1 (RAG1) protein and is a putative substrate of the RAG1 ubiquitin ligase. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012] |
Chromosome 1 |
Chromosome 3 |
Locus 1 |
3q21.1 |
Coordinates 1 |
This gene maps to 122140747-122233786 in GRCh37 coordinates. |
Gene Name 2 |
Guanine Monophosphate Synthase |
Gene Summary 2 |
In the de novo synthesis of purine nucleotides, IMP is the branch point metabolite at which point the pathway diverges to the synthesis of either guanine or adenine nucleotides. In the guanine nucleotide pathway, there are 2 enzymes involved in converting IMP to GMP, namely IMP dehydrogenase (IMPD1), which catalyzes the oxidation of IMP to XMP, and GMP synthetase, which catalyzes the amination of XMP to GMP. [provided by RefSeq, Jul 2008] |
Chromosome 2 |
Chromosome3 |
Locus 2 |
3q25.31 |
Coordinates 2 |
This gene maps to 155588324-155655520 in GRCh37 coordinates. |
Associated Diseases |
Lung Adenocarcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
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1 |
RE; RE
|
GFFP-KPNA1/GMPS-06463-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-KPNA1/GMPS-06463-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-KPNA1/GMPS-06463-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-KPNA1/GMPS-06463-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-KPNA1/GMPS-06463-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-KPNA1/GMPS-06463-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-KPNA1/GMPS-06463-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-KPNA1/GMPS-06463-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-KPNA1/GMPS-06463-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-KPNA1/GMPS-06463-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-KPNA1/GMPS-06463-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-KPNA1/GMPS-06463-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-KPNA1/GMPS-06463-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-KPNA1/GMPS-06463-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-KPNA1/GMPS-06463-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-KPNA1/GMPS-06463-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-KPNA1/GMPS-06463-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-KPNA1/GMPS-06463-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-KPNA1/GMPS-06463-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-KPNA1/GMPS-06463-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-KPNA1/GMPS-06463-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-KPNA1/GMPS-06463-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-KPNA1/GMPS-06463-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-KPNA1/GMPS-06463-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-KPNA1/GMPS-06463-AQAQ |
467nm;467nm |
418nm;418nm |
|
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