KIT-HOPX Gene Fusion FISH Probe
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Catalog: |
GFFP-KIT/HOPX-06219 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The KIT-HOPX Gene Fusion FISH Probecan detect the fusion of KIT and HOPX genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
KIT-HOPX Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
KIT Proto-oncogene Receptor Tyrosine Kinase |
Gene Summary 1 |
This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
Chromosome 1 |
Chromosome 4 |
Locus 1 |
4q12 |
Coordinates 1 |
This gene maps to 55524094-55606881 in GRCh37 coordinates. |
Gene Name 2 |
HOP Homeobox |
Gene Summary 2 |
The protein encoded by this gene is a homeodomain protein that lacks certain conserved residues required for DNA binding. It was reported that choriocarcinoma cell lines and tissues failed to express this gene, which suggested the possible involvement of this gene in malignant conversion of placental trophoblasts. Studies in mice suggest that this protein may interact with serum response factor (SRF) and modulate SRF-dependent cardiac-specific gene expression and cardiac development. Multiple alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Feb 2009] |
Chromosome 2 |
Chromosome4 |
Locus 2 |
4q12 |
Coordinates 2 |
This gene maps to 57514153-57547872 in GRCh37 coordinates. |
Associated Diseases |
Brain Lower Grade Glioma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-KIT/HOPX-06219-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-KIT/HOPX-06219-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-KIT/HOPX-06219-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-KIT/HOPX-06219-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-KIT/HOPX-06219-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-KIT/HOPX-06219-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-KIT/HOPX-06219-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-KIT/HOPX-06219-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-KIT/HOPX-06219-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-KIT/HOPX-06219-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-KIT/HOPX-06219-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-KIT/HOPX-06219-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-KIT/HOPX-06219-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-KIT/HOPX-06219-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-KIT/HOPX-06219-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-KIT/HOPX-06219-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-KIT/HOPX-06219-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-KIT/HOPX-06219-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-KIT/HOPX-06219-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-KIT/HOPX-06219-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-KIT/HOPX-06219-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-KIT/HOPX-06219-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-KIT/HOPX-06219-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-KIT/HOPX-06219-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-KIT/HOPX-06219-AQAQ |
467nm;467nm |
418nm;418nm |
|
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