KIF22-PRKCB Gene Fusion FISH Probe
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Catalog: |
GFFP-KIF22/PRKCB-06238 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The KIF22-PRKCB Gene Fusion FISH Probecan detect the fusion of KIF22 and PRKCB genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
KIF22-PRKCB Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Kinesin Family Member 22 |
Gene Summary 1 |
The protein encoded by this gene is a member of the kinesin-like protein family. The family members are microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. The C-terminal half of this protein has been shown to bind DNA. Studies with the Xenopus homolog suggests its essential role in metaphase chromosome alignment and maintenance. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012] |
Chromosome 1 |
Chromosome 16 |
Locus 1 |
16p11.2 |
Coordinates 1 |
This gene maps to 29802057-29816706 in GRCh37 coordinates. |
Gene Name 2 |
Protein Kinase C Beta |
Gene Summary 2 |
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption. Studies in mice also suggest that this kinase may also regulate neuronal functions and correlate fear-induced conflict behavior after stress. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008] |
Chromosome 2 |
Chromosome16 |
Locus 2 |
16p12.2-p12.1 |
Coordinates 2 |
This gene maps to 23847299-24231932 in GRCh37 coordinates. |
Associated Diseases |
Esophageal Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-KIF22/PRKCB-06238-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-KIF22/PRKCB-06238-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-KIF22/PRKCB-06238-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-KIF22/PRKCB-06238-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-KIF22/PRKCB-06238-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-KIF22/PRKCB-06238-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-KIF22/PRKCB-06238-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-KIF22/PRKCB-06238-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-KIF22/PRKCB-06238-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-KIF22/PRKCB-06238-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-KIF22/PRKCB-06238-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-KIF22/PRKCB-06238-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-KIF22/PRKCB-06238-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-KIF22/PRKCB-06238-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-KIF22/PRKCB-06238-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-KIF22/PRKCB-06238-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-KIF22/PRKCB-06238-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-KIF22/PRKCB-06238-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-KIF22/PRKCB-06238-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-KIF22/PRKCB-06238-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-KIF22/PRKCB-06238-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-KIF22/PRKCB-06238-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-KIF22/PRKCB-06238-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-KIF22/PRKCB-06238-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-KIF22/PRKCB-06238-AQAQ |
467nm;467nm |
418nm;418nm |
|
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