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KIAA0100-SEZ6 Gene Fusion FISH Probe

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Catalog: GFFP-KIAA0100/SEZ6-06105
Classification: Gene Fusion FISH Probes
Description: The KIAA0100-SEZ6 Gene Fusion FISH Probecan detect the fusion of KIAA0100 and SEZ6 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: KIAA0100-SEZ6 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Seizure Related 6 Homolog
Gene Summary 1 This gene was initially characterized in human as having high expression levels in breast carcinomas and breast cancer cell lines. This gene also has increased expression in prostrate cancer cells relative to normal prostrate tissues. Expression of this gene is negatively regulated by direct binding of the microRNA miR-195 to its 3' UTR. miR-195 has been shown to modulate the invasiveness of prostrate cancer cells and xenograft metastases by downgrading expression of this gene. In mouse, the protein encoded by this gene was identified as an antigen on acute monocytic leukemia cells. In human, alternative splicing results in multiple transcript variants encoding distinct isoforms; some of these isoforms are predicted to contain an RNA pol II promoter FMP27 protein domain and a Golgi-body-localization APT1 domain. [provided by RefSeq, Apr 2017]
Chromosome 1 Chromosome 17
Locus 1 17q11.2
Coordinates 1 This gene maps to 26941457-26972177 in GRCh37 coordinates.
Gene Summary 2 The protein encoded by this gene is thought to contain five cysteine-rich motifs that are similar to sushi domains, as well as two domains similar to the amino terminal half of the CUB (for complement C1r/C1s, Uegf, Bmp1) domain. Mutations in this gene have been associated with febrile seizures. [provided by RefSeq, Jul 2016]
Chromosome 2 Chromosome17
Locus 2 17q11.2
Coordinates 2 This gene maps to 27281946-27333081 in GRCh37 coordinates.
Associated Diseases Lung Squamous Cell Carcinoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-KIAA0100/SEZ6-06105-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-KIAA0100/SEZ6-06105-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-KIAA0100/SEZ6-06105-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-KIAA0100/SEZ6-06105-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-KIAA0100/SEZ6-06105-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-KIAA0100/SEZ6-06105-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-KIAA0100/SEZ6-06105-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-KIAA0100/SEZ6-06105-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-KIAA0100/SEZ6-06105-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-KIAA0100/SEZ6-06105-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-KIAA0100/SEZ6-06105-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-KIAA0100/SEZ6-06105-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-KIAA0100/SEZ6-06105-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-KIAA0100/SEZ6-06105-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-KIAA0100/SEZ6-06105-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-KIAA0100/SEZ6-06105-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-KIAA0100/SEZ6-06105-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-KIAA0100/SEZ6-06105-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-KIAA0100/SEZ6-06105-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-KIAA0100/SEZ6-06105-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-KIAA0100/SEZ6-06105-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-KIAA0100/SEZ6-06105-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-KIAA0100/SEZ6-06105-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-KIAA0100/SEZ6-06105-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-KIAA0100/SEZ6-06105-AQAQ 467nm;467nm 418nm;418nm

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