KIAA0100-SEZ6 Gene Fusion FISH Probe
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Catalog: |
GFFP-KIAA0100/SEZ6-06105 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The KIAA0100-SEZ6 Gene Fusion FISH Probecan detect the fusion of KIAA0100 and SEZ6 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
KIAA0100-SEZ6 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Seizure Related 6 Homolog |
Gene Summary 1 |
This gene was initially characterized in human as having high expression levels in breast carcinomas and breast cancer cell lines. This gene also has increased expression in prostrate cancer cells relative to normal prostrate tissues. Expression of this gene is negatively regulated by direct binding of the microRNA miR-195 to its 3' UTR. miR-195 has been shown to modulate the invasiveness of prostrate cancer cells and xenograft metastases by downgrading expression of this gene. In mouse, the protein encoded by this gene was identified as an antigen on acute monocytic leukemia cells. In human, alternative splicing results in multiple transcript variants encoding distinct isoforms; some of these isoforms are predicted to contain an RNA pol II promoter FMP27 protein domain and a Golgi-body-localization APT1 domain. [provided by RefSeq, Apr 2017] |
Chromosome 1 |
Chromosome 17 |
Locus 1 |
17q11.2 |
Coordinates 1 |
This gene maps to 26941457-26972177 in GRCh37 coordinates. |
Gene Summary 2 |
The protein encoded by this gene is thought to contain five cysteine-rich motifs that are similar to sushi domains, as well as two domains similar to the amino terminal half of the CUB (for complement C1r/C1s, Uegf, Bmp1) domain. Mutations in this gene have been associated with febrile seizures. [provided by RefSeq, Jul 2016] |
Chromosome 2 |
Chromosome17 |
Locus 2 |
17q11.2 |
Coordinates 2 |
This gene maps to 27281946-27333081 in GRCh37 coordinates. |
Associated Diseases |
Lung Squamous Cell Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-KIAA0100/SEZ6-06105-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-KIAA0100/SEZ6-06105-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-KIAA0100/SEZ6-06105-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-KIAA0100/SEZ6-06105-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-KIAA0100/SEZ6-06105-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-KIAA0100/SEZ6-06105-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-KIAA0100/SEZ6-06105-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-KIAA0100/SEZ6-06105-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-KIAA0100/SEZ6-06105-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-KIAA0100/SEZ6-06105-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-KIAA0100/SEZ6-06105-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-KIAA0100/SEZ6-06105-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-KIAA0100/SEZ6-06105-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-KIAA0100/SEZ6-06105-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-KIAA0100/SEZ6-06105-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-KIAA0100/SEZ6-06105-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-KIAA0100/SEZ6-06105-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-KIAA0100/SEZ6-06105-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-KIAA0100/SEZ6-06105-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-KIAA0100/SEZ6-06105-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-KIAA0100/SEZ6-06105-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-KIAA0100/SEZ6-06105-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-KIAA0100/SEZ6-06105-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-KIAA0100/SEZ6-06105-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-KIAA0100/SEZ6-06105-AQAQ |
467nm;467nm |
418nm;418nm |
|
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