KDM5A-RAE1 Gene Fusion FISH Probe
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Catalog: |
GFFP-KDM5A/RAE1-06126 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The KDM5A-RAE1 Gene Fusion FISH Probecan detect the fusion of KDM5A and RAE1 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
KDM5A-RAE1 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Lysine Demethylase 5A |
Gene Summary 1 |
This gene encodes a member of the Jumonji, AT-rich interactive domain 1 (JARID1) histone demethylase protein family. The encoded protein plays a role in gene regulation through the histone code by specifically demethylating lysine 4 of histone H3. The encoded protein interacts with many other proteins, including retinoblastoma protein, and is implicated in the transcriptional regulation of Hox genes and cytokines. This gene may play a role in tumor progression. [provided by RefSeq, Aug 2013] |
Chromosome 1 |
Chromosome 12 |
Locus 1 |
12p13.33 |
Coordinates 1 |
This gene maps to 389222-498620 in GRCh37 coordinates. |
Gene Name 2 |
Ribonucleic Acid Export 1 |
Gene Summary 2 |
Mutations in the Schizosaccharomyces pombe Rae1 and Saccharomyces cerevisiae Gle2 genes have been shown to result in accumulation of poly(A)-containing mRNA in the nucleus, suggesting that the encoded proteins are involved in RNA export. The protein encoded by this gene is a homolog of yeast Rae1. It contains four WD40 motifs, and has been shown to localize to distinct foci in the nucleoplasm, to the nuclear rim, and to meshwork-like structures throughout the cytoplasm. This gene is thought to be involved in nucleocytoplasmic transport, and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] |
Chromosome 2 |
Chromosome20 |
Locus 2 |
20q13.31 |
Coordinates 2 |
This gene maps to 55926144-55953519 in GRCh37 coordinates. |
Associated Diseases |
Lung Adenocarcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-KDM5A/RAE1-06126-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-KDM5A/RAE1-06126-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-KDM5A/RAE1-06126-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-KDM5A/RAE1-06126-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-KDM5A/RAE1-06126-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-KDM5A/RAE1-06126-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-KDM5A/RAE1-06126-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-KDM5A/RAE1-06126-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-KDM5A/RAE1-06126-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-KDM5A/RAE1-06126-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-KDM5A/RAE1-06126-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-KDM5A/RAE1-06126-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-KDM5A/RAE1-06126-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-KDM5A/RAE1-06126-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-KDM5A/RAE1-06126-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-KDM5A/RAE1-06126-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-KDM5A/RAE1-06126-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-KDM5A/RAE1-06126-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-KDM5A/RAE1-06126-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-KDM5A/RAE1-06126-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-KDM5A/RAE1-06126-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-KDM5A/RAE1-06126-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-KDM5A/RAE1-06126-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-KDM5A/RAE1-06126-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-KDM5A/RAE1-06126-AQAQ |
467nm;467nm |
418nm;418nm |
|
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