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INPP5K-RPA1 Gene Fusion FISH Probe

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Catalog: GFFP-INPP5K/RPA1-05773
Classification: Gene Fusion FISH Probes
Description: The INPP5K-RPA1 Gene Fusion FISH Probecan detect the fusion of INPP5K and RPA1 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: INPP5K-RPA1 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Replication Protein A1
Gene Summary 1 This gene encodes the largest subunit of the heterotrimeric Replication Protein A (RPA) complex, which binds to single-stranded DNA (ssDNA), forming a nucleoprotein complex that plays an important role in DNA metabolism, being involved in DNA replication, repair, recombination, telomere maintenance, and co-ordinating the cellular response to DNA damage through activation of the ataxia telangiectasia and Rad3-related protein (ATR) kinase. The nucleoprotein complex protects the single-stranded DNA from nucleases, prevents formation of secondary structures that would interfere with repair, and co-ordinates the recruitment and departure of different genome maintenance factors. This subunit contains four oligonucleotide/oligosaccharide-binding (OB) domains, though the majority of ssDNA binding occurs in two of these domains. The heterotrimeric complex has two different modes of ssDNA binding, a low-affinity and high-affinity mode, determined by which ssDNA binding domains are utilized. The different binding modes differ in the length of DNA bound and in the proteins with which it interacts, thereby playing a role in regulating different genomic maintenance pathways. [provided by RefSeq, Sep 2017]
Chromosome 1 Chromosome 17
Locus 1 17p13.3
Coordinates 1 This gene maps to 1733272-1802848 in GRCh37 coordinates.
Gene Name 2 Inositol Polyphosphate-5-phosphatase K
Gene Summary 2 This gene encodes a protein with 5-phosphatase activity toward polyphosphate inositol. The protein localizes to the cytosol in regions lacking actin stress fibers. It is thought that this protein may negatively regulate the actin cytoskeleton. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2008]
Chromosome 2 Chromosome17
Locus 2 17p13.3
Coordinates 2 This gene maps to 1397870-1420182 in GRCh37 coordinates.
Associated Diseases Cholangiocarcinoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-INPP5K/RPA1-05773-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-INPP5K/RPA1-05773-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-INPP5K/RPA1-05773-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-INPP5K/RPA1-05773-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-INPP5K/RPA1-05773-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-INPP5K/RPA1-05773-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-INPP5K/RPA1-05773-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-INPP5K/RPA1-05773-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-INPP5K/RPA1-05773-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-INPP5K/RPA1-05773-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-INPP5K/RPA1-05773-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-INPP5K/RPA1-05773-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-INPP5K/RPA1-05773-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-INPP5K/RPA1-05773-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-INPP5K/RPA1-05773-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-INPP5K/RPA1-05773-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-INPP5K/RPA1-05773-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-INPP5K/RPA1-05773-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-INPP5K/RPA1-05773-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-INPP5K/RPA1-05773-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-INPP5K/RPA1-05773-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-INPP5K/RPA1-05773-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-INPP5K/RPA1-05773-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-INPP5K/RPA1-05773-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-INPP5K/RPA1-05773-AQAQ 467nm;467nm 418nm;418nm

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