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IMPA1-RSPO2 Gene Fusion FISH Probe

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Catalog: GFFP-IMPA1/RSPO2-05800
Classification: Gene Fusion FISH Probes
Description: The IMPA1-RSPO2 Gene Fusion FISH Probecan detect the fusion of IMPA1 and RSPO2 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: IMPA1-RSPO2 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Inositol Monophosphatase 1
Gene Summary 1 This gene encodes an enzyme that dephosphorylates myo-inositol monophosphate to generate free myo-inositol, a precursor of phosphatidylinositol, and is therefore an important modulator of intracellular signal transduction via the production of the second messengers myoinositol 1,4,5-trisphosphate and diacylglycerol. This enzyme can also use myo-inositol-1,3-diphosphate, myo-inositol-1,4-diphosphate, scyllo-inositol-phosphate, glucose-1-phosphate, glucose-6-phosphate, fructose-1-phosphate, beta-glycerophosphate, and 2'-AMP as substrates. This enzyme shows magnesium-dependent phosphatase activity and is inhibited by therapeutic concentrations of lithium. Inhibition of inositol monophosphate hydroylosis and subsequent depletion of inositol for phosphatidylinositol synthesis may explain the anti-manic and anti-depressive effects of lithium administered to treat bipolar disorder. Alternative splicing results in multiple transcript variants encoding distinct isoforms. A pseudogene of this gene is also present on chromosome 8q21.13. [provided by RefSeq, Dec 2014]
Chromosome 1 Chromosome 8
Locus 1 8q21.13
Coordinates 1 This gene maps to 82569150-82598589 in GRCh37 coordinates.
Gene Name 2 R-spondin 2
Gene Summary 2 This gene encodes a member of the R-spondin family of proteins. These proteins are secreted ligands of leucine-rich repeat containing G protein-coupled receptors that enhance Wnt signaling through the inhibition of ubiquitin E3 ligases. A chromosomal translocation including this locus that results in the formation of a gene fusion has been identified in multiple human cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
Chromosome 2 Chromosome8
Locus 2 8q23.1
Coordinates 2 This gene maps to 108911543-109095913 in GRCh37 coordinates.
Associated Diseases Prostate Adenocarcinoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-IMPA1/RSPO2-05800-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-IMPA1/RSPO2-05800-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-IMPA1/RSPO2-05800-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-IMPA1/RSPO2-05800-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-IMPA1/RSPO2-05800-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-IMPA1/RSPO2-05800-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-IMPA1/RSPO2-05800-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-IMPA1/RSPO2-05800-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-IMPA1/RSPO2-05800-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-IMPA1/RSPO2-05800-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-IMPA1/RSPO2-05800-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-IMPA1/RSPO2-05800-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-IMPA1/RSPO2-05800-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-IMPA1/RSPO2-05800-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-IMPA1/RSPO2-05800-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-IMPA1/RSPO2-05800-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-IMPA1/RSPO2-05800-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-IMPA1/RSPO2-05800-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-IMPA1/RSPO2-05800-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-IMPA1/RSPO2-05800-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-IMPA1/RSPO2-05800-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-IMPA1/RSPO2-05800-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-IMPA1/RSPO2-05800-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-IMPA1/RSPO2-05800-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-IMPA1/RSPO2-05800-AQAQ 467nm;467nm 418nm;418nm

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