ILF3-ATG4D Gene Fusion FISH Probe
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Catalog: |
GFFP-ILF3/ATG4D-05807 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The ILF3-ATG4D Gene Fusion FISH Probecan detect the fusion of ILF3 and ATG4D genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
ILF3-ATG4D Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Interleukin Enhancer Binding Factor 3 |
Gene Summary 1 |
This gene encodes a double-stranded RNA (dsRNA) binding protein that complexes with other proteins, dsRNAs, small noncoding RNAs, and mRNAs to regulate gene expression and stabilize mRNAs. This protein (NF90, ILF3) forms a heterodimer with a 45 kDa transcription factor (NF45, ILF2) required for T-cell expression of interleukin 2. This complex has been shown to affect the redistribution of nuclear mRNA to the cytoplasm. Knockdown of NF45 or NF90 protein retards cell growth, possibly by inhibition of mRNA stabilization. In contrast, an isoform (NF110) of this gene that is predominantly restricted to the nucleus has only minor effects on cell growth when its levels are reduced. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Dec 2014] |
Chromosome 1 |
Chromosome 19 |
Locus 1 |
19p13.2 |
Coordinates 1 |
This gene maps to 10764936-10803095 in GRCh37 coordinates. |
Gene Name 2 |
Autophagy Related 4D Cysteine Peptidase |
Gene Summary 2 |
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene belongs to the autophagy-related protein 4 (Atg4) family of C54 endopeptidases. Members of this family encode proteins that play a role in the biogenesis of autophagosomes, which sequester the cytosol and organelles for degradation by lysosomes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] |
Chromosome 2 |
Chromosome19 |
Locus 2 |
19p13.2 |
Coordinates 2 |
This gene maps to 10654646-10664094 in GRCh37 coordinates. |
Associated Diseases |
Bladder Urothelial Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-ILF3/ATG4D-05807-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-ILF3/ATG4D-05807-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-ILF3/ATG4D-05807-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-ILF3/ATG4D-05807-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-ILF3/ATG4D-05807-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-ILF3/ATG4D-05807-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-ILF3/ATG4D-05807-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-ILF3/ATG4D-05807-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-ILF3/ATG4D-05807-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-ILF3/ATG4D-05807-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-ILF3/ATG4D-05807-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-ILF3/ATG4D-05807-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-ILF3/ATG4D-05807-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-ILF3/ATG4D-05807-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-ILF3/ATG4D-05807-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-ILF3/ATG4D-05807-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-ILF3/ATG4D-05807-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-ILF3/ATG4D-05807-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-ILF3/ATG4D-05807-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-ILF3/ATG4D-05807-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-ILF3/ATG4D-05807-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-ILF3/ATG4D-05807-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-ILF3/ATG4D-05807-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-ILF3/ATG4D-05807-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-ILF3/ATG4D-05807-AQAQ |
467nm;467nm |
418nm;418nm |
|
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