Gene-specific Copy Number Variation Probe-TRAF2
Add to Cart
| Catalog: |
CNVFP-TRAF2-21434 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (TRAF2). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
TRAF2 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to TRAF2 genes. This product achieves the purpose of detection by hybridizing with the TRAF2 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
TNF Receptor Associated Factor 2 |
| Gene Summary [Provided by RefSeq] |
The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from members of the TNF receptor superfamily. This protein directly interacts with TNF receptors, and forms a heterodimeric complex with TRAF1. This protein is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF1 interacts with the inhibitor-of-apoptosis proteins (IAPs), and functions as a mediator of the anti-apoptotic signals from TNF receptors. The interaction of this protein with TRADD, a TNF receptor associated apoptotic signal transducer, ensures the recruitment of IAPs for the direct inhibition of caspase activation. BIRC2/c-IAP1, an apoptosis inhibitor possessing ubiquitin ligase activity, can unbiquitinate and induce the degradation of this protein, and thus potentiate TNF-induced apoptosis. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of only one transcript has been determined. [provided by RefSeq, Jul 2008] |
| Gene Symbol |
TRAF2 |
| Location |
9q34.3 |
| Chromosome |
Chromosome9 |
| Coordinates |
This gene maps to 139780964-139821067 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-TRAF2-21434-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-TRAF2-21434-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-TRAF2-21434-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-TRAF2-21434-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-TRAF2-21434-AQ |
467nm |
418nm |
|
Other Products
