Gene-specific Copy Number Variation Probe-TOP2B
Add to Cart
| Catalog: |
CNVFP-TOP2B-21182 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (TOP2B). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
TOP2B Gene-specific copy number variation probes are mainly used to detect the copy number variation related to TOP2B genes. This product achieves the purpose of detection by hybridizing with the TOP2B gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
DNA Topoisomerase II Beta |
| Gene Summary [Provided by RefSeq] |
This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the relief of torsional stress that occurs during DNA transcription and replication. It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another, thus altering the topology of DNA. Two forms of this enzyme exist as likely products of a gene duplication event. The gene encoding this form, beta, is localized to chromosome 3 and the alpha form is localized to chromosome 17. The gene encoding this enzyme functions as the target for several anticancer agents and a variety of mutations in this gene have been associated with the development of drug resistance. Reduced activity of this enzyme may also play a role in ataxia-telangiectasia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016] |
| Gene Symbol |
TOP2B |
| Location |
3p24.2 |
| Chromosome |
Chromosome3 |
| Coordinates |
This gene maps to 25639474-25705788 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-TOP2B-21182-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-TOP2B-21182-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-TOP2B-21182-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-TOP2B-21182-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-TOP2B-21182-AQ |
467nm |
418nm |
|
Other Products
