Gene-specific Copy Number Variation Probe-TIAM1
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| Catalog: |
CNVFP-TIAM1-20883 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (TIAM1). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
TIAM1 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to TIAM1 genes. This product achieves the purpose of detection by hybridizing with the TIAM1 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
T-cell Lymphoma Invasion And Metastasis 1 |
| Gene Summary [Provided by RefSeq] |
This gene encodes a RAC1-specific guanine nucleotide exchange factor (GEF). GEFs mediate the exchange of guanosine diphosphate (GDP) for guanosine triphosphate (GTP). The binding of GTP induces a conformational change in RAC1 that allows downstream effectors to bind and transduce a signal. This gene thus regulates RAC1 signaling pathways that affect cell shape, migration, adhesion, growth, survival, and polarity, as well as influencing actin cytoskeletal formation, endocytosis, and membrane trafficking. This gene thus plays an important role in cell invasion, metastasis, and carcinogenesis. In addition to RAC1, the encoded protein activates additional Rho-like GTPases such as CDC42, RAC2, RAC3 and RHOA. This gene encodes multiple protein isoforms that experience a diverse array of intramolecular, protein-protein, and phosphorylation interactions as well as phosphoinositide binding. Both the longer and shorter isoforms have C-terminal Dbl homology (DH) and pleckstrin homology (PH) domains while only the longer isoforms of this gene have the N-terminal myristoylation site and the downstream N-terminal PH domain, ras-binding domain (RBD), and PSD-95/DlgA/ZO-1 (PDZ) domain. [provided by RefSeq, Jul 2017] |
| Gene Symbol |
TIAM1 |
| Location |
21q22.11 |
| Chromosome |
Chromosome21 |
| Coordinates |
This gene maps to 32490735-32931290 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-TIAM1-20883-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-TIAM1-20883-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-TIAM1-20883-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-TIAM1-20883-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-TIAM1-20883-AQ |
467nm |
418nm |
|
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