Gene-specific Copy Number Variation Probe-STRADA
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| Catalog: |
CNVFP-STRADA-20074 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (STRADA). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
STRADA Gene-specific copy number variation probes are mainly used to detect the copy number variation related to STRADA genes. This product achieves the purpose of detection by hybridizing with the STRADA gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
STE20-related Kinase Adaptor Alpha |
| Gene Summary [Provided by RefSeq] |
The protein encoded by this gene contains a STE20-like kinase domain, but lacks several residues that are critical for catalytic activity, so it is termed a 'pseudokinase'. The protein forms a heterotrimeric complex with serine/threonine kinase 11 (STK11, also known as LKB1) and the scaffolding protein calcium binding protein 39 (CAB39, also known as MO25). The protein activates STK11 leading to the phosphorylation of both proteins and excluding STK11 from the nucleus. The protein is necessary for STK11-induced G1 cell cycle arrest. A mutation in this gene has been shown to result in polyhydramnios, megalencephaly, and symptomatic epilepsy (PMSE) syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their full-length nature is not known. [provided by RefSeq, Sep 2009] |
| Gene Symbol |
STRADA |
| Location |
17q23.3 |
| Chromosome |
Chromosome17 |
| Coordinates |
This gene maps to 61780191-61819330 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-STRADA-20074-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-STRADA-20074-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-STRADA-20074-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-STRADA-20074-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-STRADA-20074-AQ |
467nm |
418nm |
|
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