Gene-specific Copy Number Variation Probe-SPAM1
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Catalog: |
CNVFP-SPAM1-19739 |
Classification: |
Copy Number Variation |
Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (SPAM1). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
Application: |
SPAM1 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to SPAM1 genes. This product achieves the purpose of detection by hybridizing with the SPAM1 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
Category: |
Copy Number Variation |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name |
Sperm Adhesion Molecule 1 |
Gene Summary [Provided by RefSeq] |
Hyaluronidase degrades hyaluronic acid, a major structural proteoglycan found in extracellular matrices and basement membranes. Six members of the hyaluronidase family are clustered into two tightly linked groups on chromosome 3p21.3 and 7q31.3. This gene was previously referred to as HYAL1 and HYA1 and has since been assigned the official symbol SPAM1; another family member on chromosome 3p21.3 has been assigned HYAL1. This gene encodes a GPI-anchored enzyme located on the human sperm surface and inner acrosomal membrane. This multifunctional protein is a hyaluronidase that enables sperm to penetrate through the hyaluronic acid-rich cumulus cell layer surrounding the oocyte, a receptor that plays a role in hyaluronic acid induced cell signaling, and a receptor that is involved in sperm-zona pellucida adhesion. Abnormal expression of this gene in tumors has implicated this protein in degradation of basement membranes leading to tumor invasion and metastasis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010] |
Gene Symbol |
SPAM1 |
Location |
7q31.32 |
Chromosome |
Chromosome7 |
Coordinates |
This gene maps to 123565285-123611461 in GRCh37 coordinates. |
Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
OR
|
CNVFP-SPAM1-19739-OR |
573nm |
548nm |
|
2 |
RE
|
CNVFP-SPAM1-19739-RE |
599nm |
580nm |
|
3 |
GO
|
CNVFP-SPAM1-19739-GO |
551nm |
525nm |
|
4 |
GR
|
CNVFP-SPAM1-19739-GR |
515nm |
491nm |
|
5 |
AQ
|
CNVFP-SPAM1-19739-AQ |
467nm |
418nm |
|
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