Gene-specific Copy Number Variation Probe-SENP6
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| Catalog: |
CNVFP-SENP6-18247 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (SENP6). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
SENP6 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to SENP6 genes. This product achieves the purpose of detection by hybridizing with the SENP6 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
SUMO1/sentrin Specific Peptidase 6 |
| Gene Summary [Provided by RefSeq] |
Ubiquitin-like molecules (UBLs), such as SUMO1 (UBL1; MIM 601912), are structurally related to ubiquitin (MIM 191339) and can be ligated to target proteins in a similar manner as ubiquitin. However, covalent attachment of UBLs does not result in degradation of the modified proteins. SUMO1 modification is implicated in the targeting of RANGAP1 (MIM 602362) to the nuclear pore complex, as well as in stabilization of I-kappa-B-alpha (NFKBIA; MIM 164008) from degradation by the 26S proteasome. Like ubiquitin, UBLs are synthesized as precursor proteins, with 1 or more amino acids following the C-terminal glycine-glycine residues of the mature UBL protein. Thus, the tail sequences of the UBL precursors need to be removed by UBL-specific proteases, such as SENP6, prior to their conjugation to target proteins (Kim et al., 2000 [PubMed 10799485]). SENPs also display isopeptidase activity for deconjugation of SUMO-conjugated substrates (Lima and Reverter, 2008 [PubMed 18799455]).[supplied by OMIM, Jun 2009] |
| Gene Symbol |
SENP6 |
| Location |
6q14.1 |
| Chromosome |
Chromosome6 |
| Coordinates |
This gene maps to 76311621-76427994 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-SENP6-18247-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-SENP6-18247-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-SENP6-18247-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-SENP6-18247-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-SENP6-18247-AQ |
467nm |
418nm |
|
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