Gene-specific Copy Number Variation Probe-RAG2
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| Catalog: |
CNVFP-RAG2-17119 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (RAG2). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
RAG2 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to RAG2 genes. This product achieves the purpose of detection by hybridizing with the RAG2 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Recombination Activating 2 |
| Gene Summary [Provided by RefSeq] |
This gene encodes a protein that is involved in the initiation of V(D)J recombination during B and T cell development. This protein forms a complex with the product of the adjacent recombination activating gene 1, and this complex can form double-strand breaks by cleaving DNA at conserved recombination signal sequences. The recombination activating gene 1 component is thought to contain most of the catalytic activity, while the N-terminal of the recombination activating gene 2 component is thought to form a six-bladed propeller in the active core that serves as a binding scaffold for the tight association of the complex with DNA. A C-terminal plant homeodomain finger-like motif in this protein is necessary for interactions with chromatin components, specifically with histone H3 that is trimethylated at lysine 4. Mutations in this gene cause Omenn syndrome, a form of severe combined immunodeficiency associated with autoimmune-like symptoms. [provided by RefSeq, Jul 2008] |
| Gene Symbol |
RAG2 |
| Location |
11p12 |
| Chromosome |
Chromosome11 |
| Coordinates |
This gene maps to 36613492-36619829 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-RAG2-17119-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-RAG2-17119-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-RAG2-17119-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-RAG2-17119-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-RAG2-17119-AQ |
467nm |
418nm |
|
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