Gene-specific Copy Number Variation Probe-PYGL
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| Catalog: |
CNVFP-PYGL-16922 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (PYGL). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
PYGL Gene-specific copy number variation probes are mainly used to detect the copy number variation related to PYGL genes. This product achieves the purpose of detection by hybridizing with the PYGL gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Glycogen Phosphorylase L |
| Gene Summary [Provided by RefSeq] |
This gene encodes a homodimeric protein that catalyses the cleavage of alpha-1,4-glucosidic bonds to release glucose-1-phosphate from liver glycogen stores. This protein switches from inactive phosphorylase B to active phosphorylase A by phosphorylation of serine residue 15. Activity of this enzyme is further regulated by multiple allosteric effectors and hormonal controls. Humans have three glycogen phosphorylase genes that encode distinct isozymes that are primarily expressed in liver, brain and muscle, respectively. The liver isozyme serves the glycemic demands of the body in general while the brain and muscle isozymes supply just those tissues. In glycogen storage disease type VI, also known as Hers disease, mutations in liver glycogen phosphorylase inhibit the conversion of glycogen to glucose and results in moderate hypoglycemia, mild ketosis, growth retardation and hepatomegaly. Alternative splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Feb 2011] |
| Gene Symbol |
PYGL |
| Location |
14q22.1 |
| Chromosome |
Chromosome14 |
| Coordinates |
This gene maps to 51371934-51411248 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-PYGL-16922-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-PYGL-16922-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-PYGL-16922-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-PYGL-16922-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-PYGL-16922-AQ |
467nm |
418nm |
|
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