Gene-specific Copy Number Variation Probe-OAZ3
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| Catalog: |
CNVFP-OAZ3-14575 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (OAZ3). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
OAZ3 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to OAZ3 genes. This product achieves the purpose of detection by hybridizing with the OAZ3 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Ornithine Decarboxylase Antizyme 3 |
| Gene Summary [Provided by RefSeq] |
The protein encoded by this gene belongs to the ornithine decarboxylase antizyme family, which plays a role in cell growth and proliferation by regulating intracellular polyamine levels. Expression of antizymes requires +1 ribosomal frameshifting, which is enhanced by high levels of polyamines. Antizymes in turn bind to and inhibit ornithine decarboxylase (ODC), the key enzyme in polyamine biosynthesis; thus, completing the auto-regulatory circuit. This gene encodes antizyme 3, the third member of the antizyme family. Like antizymes 1 and 2, antizyme 3 inhibits ODC activity and polyamine uptake; however, it does not stimulate ODC degradation. Also, while antizymes 1 and 2 have broad tissue distribution, expression of antizyme 3 is restricted to haploid germ cells in testis, suggesting a distinct role for this antizyme in spermiogenesis. Antizyme 3 gene knockout studies showed that homozygous mutant male mice were infertile, and indicated the likely role of this antizyme in the formation of a rigid connection between the sperm head and tail during spermatogenesis. Alternatively spliced transcript variants encoding different isoforms, including one resulting from the use of non-AUG (CUG) translation initiation codon, have been found for this gene. [provided by RefSeq, Dec 2014] |
| Gene Symbol |
OAZ3 |
| Location |
1q21.3 |
| Chromosome |
Chromosome1 |
| Coordinates |
This gene maps to 151735444-151743806 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-OAZ3-14575-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-OAZ3-14575-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-OAZ3-14575-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-OAZ3-14575-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-OAZ3-14575-AQ |
467nm |
418nm |
|
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