Gene-specific Copy Number Variation Probe-A2M
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| Catalog: |
CNVFP-A2M-00260 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (A2M). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
A2M Gene-specific copy number variation probes are mainly used to detect the copy number variation related to A2M genes. This product achieves the purpose of detection by hybridizing with the A2M gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Alpha-2-macroglobulin |
| Gene Summary [Provided by RefSeq] |
The protein encoded by this gene is a protease inhibitor and cytokine transporter. It uses a bait-and-trap mechanism to inhibit a broad spectrum of proteases, including trypsin, thrombin and collagenase. It can also inhibit inflammatory cytokines, and it thus disrupts inflammatory cascades. Mutations in this gene are a cause of alpha-2-macroglobulin deficiency. This gene is implicated in Alzheimer's disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. A related pseudogene, which is also located on the p arm of chromosome 12, has been identified. [provided by RefSeq, Nov 2016] |
| Gene Symbol |
A2M |
| Location |
12p13.31 |
| Chromosome |
Chromosome12 |
| Coordinates |
This gene maps to 9220303-9268558 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-A2M-00260-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-A2M-00260-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-A2M-00260-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-A2M-00260-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-A2M-00260-AQ |
467nm |
418nm |
|
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