Gene-specific Break Apart Probe-ACER1
Add to Cart
| Catalog: |
GBAFP-ACER1-00004 |
| Classification: |
Gene-specific Break Apart Probes |
| Description: |
Our Gene-specific Break Apart Probes usually target the flanks of the target gene (ACER1). Due to this design method, our probe products can detect chromosomal rearrangements, such as translocations, by FISH.The product usually consists of a reagent combination composed of a probe with a selected dye color and a hybridization reagent. |
| Application: |
ACER1 Gene-specific Break Apart Probe is designed to detect potential ACER1 rearrangements. This probe has been confirmed on the metaphase and interphase chromosomes by FISH. We provide a variety of dye color combinations for Break Apart Probes for customers to choose from. Probe products not only provide some classic color combinations, but also provide customized probe services. |
| Category: |
Gene-specific Break Apart Probe |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
Within 10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Alkaline Ceramidase 1 |
| Gene Summary [Provided by RefSeq] |
Ceramides are synthesized during epidermal differentiation and accumulate within the interstices of the stratum corneum, where they represent critical components of the epidermal permeability barrier. Excess cellular ceramide can trigger antimitogenic signals and induce apoptosis, and the ceramide metabolites sphingosine and sphingosine-1-phosphate (S1P) are important bioregulatory molecules. Ceramide hydrolysis in the nucleated cell layers regulates keratinocyte proliferation and apoptosis in response to external stress. Ceramide hydrolysis also occurs at the stratum corneum, releasing free sphingoid base that functions as an endogenous antimicrobial agent. ACER1 is highly expressed in epidermis and catalyzes the hydrolysis of very long chain ceramides to generate sphingosine (Houben et al., 2006 [PubMed 16477081]; Sun et al., 2008 [PubMed 17713573]).[supplied by OMIM, Jul 2010] |
| Gene Symbol |
ACER1 |
| Location |
19p13.3 |
| Chromosome |
Chromosome19 |
| Coordinates |
This gene maps to 6306509-6333640 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
GR
OR
AQ
OR
GO
GR
GO
RE
GR
GO
GR
RE
OR
GR
RE
GO
RE
GR
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
GR; OR
|
GBAFP-ACER1-00004-GROR |
515nm;573nm |
491nm;548nm |
|
| 2 |
AQ; OR
|
GBAFP-ACER1-00004-AQOR |
467nm;573nm |
418nm;548nm |
|
| 3 |
GO; GR
|
GBAFP-ACER1-00004-GOGR |
551nm;515nm |
525nm;491nm |
|
| 4 |
GO; RE
|
GBAFP-ACER1-00004-GORE |
551nm;599nm |
525nm;580nm |
|
| 5 |
GR; GO
|
GBAFP-ACER1-00004-GRGO |
515nm;551nm |
491nm;525nm |
|
| 6 |
GR; RE
|
GBAFP-ACER1-00004-GRRE |
515nm;599nm |
491nm;580nm |
|
| 7 |
OR; GR
|
GBAFP-ACER1-00004-ORGR |
573nm;515nm |
548nm;491nm |
|
| 8 |
RE; GO
|
GBAFP-ACER1-00004-REGO |
599nm;551nm |
580nm;525nm |
|
| 9 |
RE; GR
|
GBAFP-ACER1-00004-REGR |
599nm;515nm |
580nm;491nm |
|
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