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Gene-specific Break Apart Probe-ACER1

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Catalog: GBAFP-ACER1-00004
Classification: Gene-specific Break Apart Probes
Description: Our Gene-specific Break Apart Probes usually target the flanks of the target gene (ACER1). Due to this design method, our probe products can detect chromosomal rearrangements, such as translocations, by FISH.The product usually consists of a reagent combination composed of a probe with a selected dye color and a hybridization reagent.
Application: ACER1 Gene-specific Break Apart Probe is designed to detect potential ACER1 rearrangements. This probe has been confirmed on the metaphase and interphase chromosomes by FISH. We provide a variety of dye color combinations for Break Apart Probes for customers to choose from. Probe products not only provide some classic color combinations, but also provide customized probe services.
Category: Gene-specific Break Apart Probe
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: Within 10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name Alkaline Ceramidase 1
Gene Summary [Provided by RefSeq] Ceramides are synthesized during epidermal differentiation and accumulate within the interstices of the stratum corneum, where they represent critical components of the epidermal permeability barrier. Excess cellular ceramide can trigger antimitogenic signals and induce apoptosis, and the ceramide metabolites sphingosine and sphingosine-1-phosphate (S1P) are important bioregulatory molecules. Ceramide hydrolysis in the nucleated cell layers regulates keratinocyte proliferation and apoptosis in response to external stress. Ceramide hydrolysis also occurs at the stratum corneum, releasing free sphingoid base that functions as an endogenous antimicrobial agent. ACER1 is highly expressed in epidermis and catalyzes the hydrolysis of very long chain ceramides to generate sphingosine (Houben et al., 2006 [PubMed 16477081]; Sun et al., 2008 [PubMed 17713573]).[supplied by OMIM, Jul 2010]
Gene Symbol ACER1
Location 19p13.3
Chromosome Chromosome19
Coordinates This gene maps to 6306509-6333640 in GRCh37 coordinates.
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 GR; OR GBAFP-ACER1-00004-GROR 515nm;573nm 491nm;548nm
2 AQ; OR GBAFP-ACER1-00004-AQOR 467nm;573nm 418nm;548nm
3 GO; GR GBAFP-ACER1-00004-GOGR 551nm;515nm 525nm;491nm
4 GO; RE GBAFP-ACER1-00004-GORE 551nm;599nm 525nm;580nm
5 GR; GO GBAFP-ACER1-00004-GRGO 515nm;551nm 491nm;525nm
6 GR; RE GBAFP-ACER1-00004-GRRE 515nm;599nm 491nm;580nm
7 OR; GR GBAFP-ACER1-00004-ORGR 573nm;515nm 548nm;491nm
8 RE; GO GBAFP-ACER1-00004-REGO 599nm;551nm 580nm;525nm
9 RE; GR GBAFP-ACER1-00004-REGR 599nm;515nm 580nm;491nm

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