CD274-IGFBPL1 Gene Fusion FISH Probe
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Catalog: |
GFFP-CD274/IGFBPL1-02129 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The CD274-IGFBPL1 Gene Fusion FISH Probecan detect the fusion of CD274 and IGFBPL1 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
CD274-IGFBPL1 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
CD274 Molecule |
Gene Summary 1 |
This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue, this interaction is important for preventing autoimmunity by maintaining homeostasis of the immune response. In tumor microenvironments, this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Expression of this gene in tumor cells is considered to be prognostic in many types of human malignancies, including colon cancer and renal cell carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015] |
Chromosome 1 |
Chromosome 9 |
Locus 1 |
9p24.1 |
Coordinates 1 |
This gene maps to 5450502-5470567 in GRCh37 coordinates. |
Gene Name 2 |
Insulin Like Growth Factor Binding Protein Like 1 |
Chromosome 2 |
Chromosome9 |
Locus 2 |
9p13.1 |
Coordinates 2 |
This gene maps to 38408990-38424444 in GRCh37 coordinates. |
Associated Diseases |
Stomach Adenocarcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
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1 |
RE; RE
|
GFFP-CD274/IGFBPL1-02129-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-CD274/IGFBPL1-02129-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-CD274/IGFBPL1-02129-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-CD274/IGFBPL1-02129-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-CD274/IGFBPL1-02129-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-CD274/IGFBPL1-02129-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-CD274/IGFBPL1-02129-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-CD274/IGFBPL1-02129-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-CD274/IGFBPL1-02129-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-CD274/IGFBPL1-02129-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-CD274/IGFBPL1-02129-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-CD274/IGFBPL1-02129-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-CD274/IGFBPL1-02129-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-CD274/IGFBPL1-02129-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-CD274/IGFBPL1-02129-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-CD274/IGFBPL1-02129-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-CD274/IGFBPL1-02129-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-CD274/IGFBPL1-02129-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-CD274/IGFBPL1-02129-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-CD274/IGFBPL1-02129-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-CD274/IGFBPL1-02129-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-CD274/IGFBPL1-02129-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-CD274/IGFBPL1-02129-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-CD274/IGFBPL1-02129-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-CD274/IGFBPL1-02129-AQAQ |
467nm;467nm |
418nm;418nm |
|
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