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ALX4-LMX1A Gene Fusion FISH Probe

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Catalog: GFFP-ALX4/LMX1A-00524
Classification: Gene Fusion FISH Probes
Description: The ALX4-LMX1A Gene Fusion FISH Probecan detect the fusion of ALX4 and LMX1A genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: ALX4-LMX1A Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 LIM Homeobox Transcription Factor 1 Alpha
Gene Summary 1 This gene encodes a homeodomain and LIM-domain containing protein. The encoded protein is a transcription factor that acts as a positive regulator of insulin gene transcription. This gene also plays a role in the development of dopamine producing neurons during embryogenesis. Mutations in this gene are associated with an increased risk of developing Parkinson's disease. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012]
Chromosome 1 Chromosome 1
Locus 1 1q23.3
Coordinates 1 This gene maps to 165171103-165325952 in GRCh37 coordinates.
Gene Name 2 ALX Homeobox 4
Gene Summary 2 This gene encodes a paired-like homeodomain transcription factor expressed in the mesenchyme of developing bones, limbs, hair, teeth, and mammary tissue. Mutations in this gene cause parietal foramina 2 (PFM2); an autosomal dominant disease characterized by deficient ossification of the parietal bones. Mutations in this gene also cause a form of frontonasal dysplasia with alopecia and hypogonadism; suggesting a role for this gene in craniofacial development, mesenchymal-epithelial communication, and hair follicle development. Deletion of a segment of chromosome 11 containing this gene, del(11)(p11p12), causes Potocki-Shaffer syndrome (PSS); a syndrome characterized by craniofacial anomalies, cognitive disability, multiple exostoses, and genital abnormalities in males. In mouse, this gene has been shown to use dual translation initiation sites located 16 codons apart. [provided by RefSeq, Oct 2009]
Chromosome 2 Chromosome11
Locus 2 11p11.2
Coordinates 2 This gene maps to 44282277-44331716 in GRCh37 coordinates.
Associated Diseases Sarcoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-ALX4/LMX1A-00524-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-ALX4/LMX1A-00524-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-ALX4/LMX1A-00524-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-ALX4/LMX1A-00524-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-ALX4/LMX1A-00524-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-ALX4/LMX1A-00524-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-ALX4/LMX1A-00524-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-ALX4/LMX1A-00524-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-ALX4/LMX1A-00524-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-ALX4/LMX1A-00524-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-ALX4/LMX1A-00524-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-ALX4/LMX1A-00524-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-ALX4/LMX1A-00524-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-ALX4/LMX1A-00524-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-ALX4/LMX1A-00524-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-ALX4/LMX1A-00524-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-ALX4/LMX1A-00524-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-ALX4/LMX1A-00524-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-ALX4/LMX1A-00524-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-ALX4/LMX1A-00524-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-ALX4/LMX1A-00524-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-ALX4/LMX1A-00524-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-ALX4/LMX1A-00524-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-ALX4/LMX1A-00524-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-ALX4/LMX1A-00524-AQAQ 467nm;467nm 418nm;418nm

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