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ACTN4-TXNDC12 Gene Fusion FISH Probe

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Catalog: GFFP-ACTN4/TXNDC12-00068
Classification: Gene Fusion FISH Probes
Description: The ACTN4-TXNDC12 Gene Fusion FISH Probe can detect the fusion of ACTN4 and TXNDC12 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: ACTN4-TXNDC12 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Actinin Alpha 4
Gene Summary 1 Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and thought to be involved in metastatic processes. Mutations in this gene have been associated with focal and segmental glomerulosclerosis. [provided by RefSeq, Jul 2008]
Chromosome 1 Chromosome 19
Locus 1 19q13.2
Coordinates 1 This gene maps to 39138266-39221171 in GRCh37 coordinates.
Gene Name 2 Thioredoxin Domain Containing 12
Gene Summary 2 This gene encodes a member of the thioredoxin superfamily. Members of this family are characterized by a conserved active motif called the thioredoxin fold that catalyzes disulfide bond formation and isomerization. This protein localizes to the endoplasmic reticulum and has a single atypical active motif. The encoded protein is mainly involved in catalyzing native disulfide bond formation and displays activity similar to protein-disulfide isomerases. This protein may play a role in defense against endoplasmic reticulum stress. Alternate splicing results in both coding and non-coding variants. [provided by RefSeq, Mar 2012]
Chromosome 2 Chromosome1
Locus 2 1p32.3
Coordinates 2 This gene maps to 52485803-52521047 in GRCh37 coordinates.
Associated Diseases Glioblastoma Multiforme
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-ACTN4/TXNDC12-00068-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-ACTN4/TXNDC12-00068-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-ACTN4/TXNDC12-00068-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-ACTN4/TXNDC12-00068-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-ACTN4/TXNDC12-00068-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-ACTN4/TXNDC12-00068-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-ACTN4/TXNDC12-00068-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-ACTN4/TXNDC12-00068-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-ACTN4/TXNDC12-00068-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-ACTN4/TXNDC12-00068-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-ACTN4/TXNDC12-00068-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-ACTN4/TXNDC12-00068-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-ACTN4/TXNDC12-00068-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-ACTN4/TXNDC12-00068-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-ACTN4/TXNDC12-00068-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-ACTN4/TXNDC12-00068-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-ACTN4/TXNDC12-00068-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-ACTN4/TXNDC12-00068-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-ACTN4/TXNDC12-00068-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-ACTN4/TXNDC12-00068-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-ACTN4/TXNDC12-00068-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-ACTN4/TXNDC12-00068-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-ACTN4/TXNDC12-00068-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-ACTN4/TXNDC12-00068-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-ACTN4/TXNDC12-00068-AQAQ 467nm;467nm 418nm;418nm

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