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ACP2-CD74 Gene Fusion FISH Probe

ACP2-CD74 Gene Fusion FISH Probe

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Catalog:	GFFP-ACP2/CD74-13808
Classification:	Gene Fusion FISH Probes
Description:	The ACP2-CD74 Gene Fusion FISH Probe can detect the fusion of ACP2 and CD74 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category:	Gene Fusion FISH Probes
Application:	ACP2-CD74 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL):	40 μL
Quantity:	20 Tests
Hybridization Solution (µL):	200 μL
Turnaround Time:	7-10 Business Days
Shipping Time:	1-2 Day Expedited Shipping
Storage Conditions:	Store at -20℃ and avoid light;
Shipping Conditions:	-20℃

Gene Details

Gene Name 1	Acid Phosphatase 2, Lysosomal
Gene Summary 1	The protein encoded by this gene belongs to the histidine acid phosphatase family, which hydrolyze orthophosphoric monoesters to alcohol and phosphate. This protein is localized to the lysosomal membrane, and is chemically and genetically distinct from the red cell acid phosphatase. Mice lacking this gene showed multiple defects, including bone structure alterations, lysosomal storage defects, and an increased tendency towards seizures. An enzymatically-inactive allele of this gene in mice showed severe growth retardation, hair-follicle abnormalities, and an ataxia-like phenotype. Alternatively spliced transcript variants have been found for this gene. A C-terminally extended isoform is also predicted to be produced by the use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism. [provided by RefSeq, Oct 2017]
Chromosome 1	Chromosome 11
Locus 1	11p12-p11
Coordinates 1	This gene maps to 47260852-47270457 in GRCh37 coordinates.
Gene Name 2	CD74 Molecule
Gene Summary 2	The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]
Chromosome 2	Chromosome5
Locus 2	5q33.1
Coordinates 2	This gene maps to 149781199-149792499 in GRCh37 coordinates.
Associated Diseases	Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma
Species	Human

Dye Colors:

RE RE RE OR RE GO RE GR RE AQ OR RE OR OR OR GO OR GR OR AQ GO RE GO OR GO GO GO GR GO AQ GR RE GR OR GR GO GR GR GR AQ AQ RE AQ OR AQ GO AQ GR AQ AQ

Order Sheet

Number	Dye Color	Order Name	Absorbance Maximum	Emission Maximum	Add to Cart
1	RE; RE	GFFP-ACP2/CD74-13808-RERE	599nm;599nm	580nm;580nm
2	RE; OR	GFFP-ACP2/CD74-13808-REOR	599nm;573nm	580nm;548nm
3	RE; GO	GFFP-ACP2/CD74-13808-REGO	599nm;551nm	580nm;525nm
4	RE; GR	GFFP-ACP2/CD74-13808-REGR	599nm;515nm	580nm;491nm
5	RE; AQ	GFFP-ACP2/CD74-13808-REAQ	599nm;467nm	580nm;418nm
6	OR; RE	GFFP-ACP2/CD74-13808-ORRE	573nm;599nm	548nm;580nm
7	OR; OR	GFFP-ACP2/CD74-13808-OROR	573nm;573nm	548nm;548nm
8	OR; GO	GFFP-ACP2/CD74-13808-ORGO	573nm;551nm	548nm;525nm
9	OR; GR	GFFP-ACP2/CD74-13808-ORGR	573nm;515nm	548nm;491nm
10	OR; AQ	GFFP-ACP2/CD74-13808-ORAQ	573nm;467nm	548nm;418nm
11	GO; RE	GFFP-ACP2/CD74-13808-GORE	551nm;599nm	525nm;580nm
12	GO; OR	GFFP-ACP2/CD74-13808-GOOR	551nm;573nm	525nm;548nm
13	GO; GO	GFFP-ACP2/CD74-13808-GOGO	551nm;551nm	525nm;525nm
14	GO; GR	GFFP-ACP2/CD74-13808-GOGR	551nm;515nm	525nm;491nm
15	GO; AQ	GFFP-ACP2/CD74-13808-GOAQ	551nm;467nm	525nm;418nm
16	GR; RE	GFFP-ACP2/CD74-13808-GRRE	515nm;599nm	491nm;580nm
17	GR; OR	GFFP-ACP2/CD74-13808-GROR	515nm;573nm	491nm;548nm
18	GR; GO	GFFP-ACP2/CD74-13808-GRGO	515nm;551nm	491nm;525nm
19	GR; GR	GFFP-ACP2/CD74-13808-GRGR	515nm;515nm	491nm;491nm
20	GR; AQ	GFFP-ACP2/CD74-13808-GRAQ	515nm;467nm	491nm;418nm
21	AQ; RE	GFFP-ACP2/CD74-13808-AQRE	467nm;599nm	418nm;580nm
22	AQ; OR	GFFP-ACP2/CD74-13808-AQOR	467nm;573nm	418nm;548nm
23	AQ; GO	GFFP-ACP2/CD74-13808-AQGO	467nm;551nm	418nm;525nm
24	AQ; GR	GFFP-ACP2/CD74-13808-AQGR	467nm;515nm	418nm;491nm
25	AQ; AQ	GFFP-ACP2/CD74-13808-AQAQ	467nm;467nm	418nm;418nm

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