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ABCC1-PRKCB Gene Fusion FISH Probe

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Catalog: GFFP-ABCC1/PRKCB-00269
Classification: Gene Fusion FISH Probes
Description: The ABCC1-PRKCB Gene Fusion FISH Probecan detect the fusion of ABCC1 and PRKCB genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: ABCC1-PRKCB Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 ATP Binding Cassette Subfamily C Member 1
Gene Summary 1 The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternatively spliced variants of this gene have been described but their full-length nature is unknown. [provided by RefSeq, Apr 2012]
Chromosome 1 Chromosome 16
Locus 1 16p13.11
Coordinates 1 This gene maps to 16043433-16236930 in GRCh37 coordinates.
Gene Name 2 Protein Kinase C Beta
Gene Summary 2 Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption. Studies in mice also suggest that this kinase may also regulate neuronal functions and correlate fear-induced conflict behavior after stress. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Chromosome 2 Chromosome16
Locus 2 16p12.2-p12.1
Coordinates 2 This gene maps to 23847299-24231932 in GRCh37 coordinates.
Associated Diseases Prostate Adenocarcinoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-ABCC1/PRKCB-00269-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-ABCC1/PRKCB-00269-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-ABCC1/PRKCB-00269-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-ABCC1/PRKCB-00269-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-ABCC1/PRKCB-00269-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-ABCC1/PRKCB-00269-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-ABCC1/PRKCB-00269-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-ABCC1/PRKCB-00269-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-ABCC1/PRKCB-00269-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-ABCC1/PRKCB-00269-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-ABCC1/PRKCB-00269-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-ABCC1/PRKCB-00269-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-ABCC1/PRKCB-00269-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-ABCC1/PRKCB-00269-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-ABCC1/PRKCB-00269-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-ABCC1/PRKCB-00269-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-ABCC1/PRKCB-00269-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-ABCC1/PRKCB-00269-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-ABCC1/PRKCB-00269-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-ABCC1/PRKCB-00269-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-ABCC1/PRKCB-00269-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-ABCC1/PRKCB-00269-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-ABCC1/PRKCB-00269-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-ABCC1/PRKCB-00269-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-ABCC1/PRKCB-00269-AQAQ 467nm;467nm 418nm;418nm

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